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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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Here are the key drug-food interactions:

  1. : Grapefruit can increase the levels of tadalafil by inhibiting PDE5, a chemical that in turn increases blood flow. This may amplify toa undesigned side effect, which minutes before sexual activity.
  2. : Though this combination may not be dangerous, it is important to distinguish between angles of action (e.g., when taken with Cialis) and cardiac effects (e.g., when taken with Cialis.
  3. : While blood pressure may decline, consuming large quantities of food or with a high-fat meal may delay the onset of action. While this combination may play a role, avoiding grapefruit or grapefruit juice while using it is recommended.

Cialis Tablet Uses

Cialis (tadalafil) Tablets are used for the treatment of male erectile dysfunction. They belong to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. It works by relaxing the muscles in the walls of blood vessels and increasing blood flow to particular areas of the body. This helps men to get and maintain an erection.

How to Use Cialis Tablet

Cialis (tadalafil) is taken about 30 minutes before sexual activity. It will not work if you are not sexually stimulated.

Side Effects of Cialis Tablet

The most common side effects include:

  • Headache
  • Upset stomach
  • Flushing
  • Nasal congestion
  • Blurred vision
  • Diarrhea
  • Back pain
  • Muscle pain
  • Dizziness
  • Nausea

Drug Interactions

Cialis (tadalafil) may interact with certain medications, including:

  • Blood pressure medications
  • Nitrates
  • Alpha-blockers
  • Antifungals
  • Antibiotics
  • Certain antidepressants
  • Diabetes medications
  • Certain blood pressure medications
  • Certain pain medications
  • Certain medications for diabetes
  • Certain medications for heart disease
  • Certain medications for high blood pressure
  • Certain medications for seizures

Before starting Cialis (tadalafil), tell your doctor or pharmacist about all your health conditions and any prescription or nonprescription medications. They may be able to help you by asking you about nonprescription medications. Cialis may also interact with certain foods and drinks, so they may ask you questions about them. Some foods and drinks may affect the way Cialis works and may increase your risk of side effects.

Do not start Cialis (tadalafil) more than directed or longer than prescribed.

If you are taking Cialis (tadalafil) to treat pulmonary arterial hypertension, tell your doctor or pharmacist.

Cialis (tadalafil) may increase the risk of side effects. Talk to your doctor about the risks and benefits before you use it. Your doctor will do some test to determine if Cialis (tadalafil) is safe for you.

The most common side effects of Cialis (tadalafil) are:

    If you have any of these side effects, stop using Cialis (tadalafil).

    If you have any more side effects, talk to your doctor about them. They may be able to help you by asking about other nonpharmacy medications you may be taking.

    Cialis (tadalafil) may interact with the following foods and drinks:

    • Alcohol
    • High-fat foods
    • High-salt or dairy products
    • High-potassium foods
    • High-fat or dairy products
    • Nonprescription medications
    • Pregnancy

    Taking Cialis (tadalafil) while pregnant may affect its safety. It is best to consult your doctor before taking Cialis (tadalafil).

    It is unknown if Cialis (tadalafil) can cause a problem with your heart and blood vessels. It may be harmful if you are not using proper heart valves.

    Cialis (tadalafil) may cause dizziness. You should avoid driving until you know how you react to this medicine. Avoid the use of alcohol while you are dizzy.

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    What is tadalafil?

    Tadalafil belongs to the class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. It works by relaxing muscles and increasing blood flow to the penis. This medications. PDE5 inhibitorsonymsExpedired stable medical challenges including pulmonary hypertension or diabetes. Curriculum for Tadalafil Clinical Research and Training Center is expected to update as needed.

    Tadalafil is a prescription medication used to treat erectile dysfunction (ED). It works by increasing blood flow to the penis. It relaxes muscles in the prostate and bladder, helping to achieve and maintain an erection. It is also used to treat pulmonary hypertension and pulmonary arterial hypertension. However, tadalafil has also been associated with sexual dysfunction, including delayed ejaculation, ejaculation disorder, and decrease in orgasm frequency. Indications for Use

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    What is the ED treatment?

    Aesizole is used to treat reflux disease (also known as chronic urodid cavernosal fibrosis). Esiz● is used to treat pulmonary arterial hypertension (PAH).

    Olanzapine is used to treat schizophrenia and bipolar disorder. Zetia is used to treat adult mania.

    Dapoxetine is a second generation antipsychotic medication used to treat schizophrenia and bipolar disorder. It work by increasing the levels of serotonin in the brain, a key indicator of mood. Dapoxetine is used to treat adult mania in some cases.

    Tadalafil is a generic medication known as atazanavir. It is available in various forms, including tablets, capsules, and oral solution. When prescribing tadalafil, it is important to consult with healthcare providers to determine which form is most suitable for individual needs.

    How long does tadalafil take to work?

    The time to take tadalafil typically lasts between 6 to 12 hours, depending on the dosage and treatment plan. Some individuals may take tadalafil for a longer duration, even after consistent use.

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    Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

    Common side effects reported from Cialis use include:

    • Headache
    • Indigestion
    • Heartburn
    • Upset stomach
    • Gas
    • Nausea
    • Flushing

    More severe side effects include:

    • Painful erections or erections that last longer than 4 hours
    • Sudden loss of vision
    • Sudden loss of hearing
    • Ringing in the ears
    • Chest pain
    • Shortness of breath
    • Painful urination
    • Increased urination frequency
    • Fainting
    • Dizziness
    • Skin rash
    • Hives
    • Facial swelling

    If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

    As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

    Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

    In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

    Read more about Cialis's effects and how it may affect you on PSA Side Effects and Prostate Cancer Initude Inreenshots. You are encouraged to report any adverse effects seek medical attention immediately.Learn more about Cialis’s side effects and serious adverse reactions - The U. S. Food and Drug Administration (FDA) has not approved Cialis for use in the United States.
  • As with all prescription medications, inform your doctor of any and all medications, prescription drugs, and supplements you are taking.
  • Cialis can cause a dangerous drop in blood pressure, which can be serious. Use caution when you use Cialis, especially if you are taking nitrates, as it can lead to a dangerous unsafe drop in blood pressure.
  • Cialis can cause a sudden loss of vision in one or both eyes. If you notice any of these reactions, contact your health care provider immediately.
  • As with all prescription medications, inform your doctor of any medical condition you are managing.

    If you experience changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

    In addition, let your health care provider know if you use nitrates or a type of alpha-blocker before starting treatment with Cialis. In addition, let your health care provider know if you are pregnant, plan to become pregnant, or are breastfeeding. If you have any questions about your health, you should contact your health care provider.

    Learn more about Cialis’s effects and serious adverse reactions - The U.
  • Use caution when you use Cialis, especially if you experience changes in your heartbeat or chest pain during sex, as these could be dangerous.